The Effect of Point-Injection of Own Blood Mixed with Gamma-Globulin on Plasma Cortisol and Cyclic Nucleotides in the Guinea Pig of Asthma

Li  Junxiong , Lao Changhui, Yu Yu ,el al (Guangdong Nanhai Hospital of Traditional Chinese Medicine , 528200; Guangzhou Universwity of Traditional Chinese Medicine and Pharmacy)

  The effects of point-injection of own blood  mixed with gamma-globulin on plasma cortisol and cyclic nucleotides in the guinea pig , plasma cortisol and cyclic nucleotides in the guinea pig of asthma were investigated.  Results  indicated that after inhalation of senstinogen in the sensitized guinea pig, plasma cortisol , cAMP and cAMP/cGMP ratio decreased obviously.  Acupoint-injection of own blood and gamma-globulin could increase plasma cortisol, cAMP levels and cAMP/cGMP ratio (P<0.001, P<0.05 and P<0.05) as compared with the model group respectively; The contents of cortisol and cAMP, and cAMP/cGMP ratio could be raised in the point-injection of simple own blood, point-injection of simple gamma-globulin and intramuscular injection  of own blood mixed with gamma –globulin, but the increases were  not so obvious.  In the experiment it is proved that point-injection therapy of own blood mixed with gamma-globulin can effectively treat asthma.

Key words ASTHMA/acupint ther ADRENAL CORTEX HORMONES /blood CYCLIC AMP/blood CYCLIC  GMP /blood  GAMA GLOBULINS /admin